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Commonly in liquid form and available in various chemical compositions, solvents are substances that dissolve solutes to form solutions. The amount and type of solute that a solvent can dissolve is dependent upon temperature and polarity.
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An analog of D-erythro-sphingosine; inhibits PKC in mixed micelle assays with 50% inhibition at 2.2 mol % making it a more potent inhibitor compared to D-erythro-sphingosine or other analogs of shorter alkyl chain length
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
D18 is an immune modulator and acts as a TLR7/8 dual agonist. It increases PD-L1 expression through epigenetic regulation, sensitizing tumors to PD-1/PD-L1 blockade. This substance is also an ADC cytotoxin used for the synthesis of ADC HE-S2 (HY-144497) and exhibits strong immune activation and anti-tumor activity, commonly used in cancer research.
Acts as a TLR7/8 dual agonist
Increases PD-L1 expression through epigenetic regulation
Sensitizes tumors to PD-1/PD-L1 blockade
Utilized as an ADC cytotoxin for ADC HE-S2 synthesis
Exhibits strong immune activation and anti-tumor activity
Used in cancer research, including colon cancer
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More